Research Article
Issue Date: June 1992
Published Online: June 01, 1992
Updated: April 30, 2020
Autistic Disorder: A Neuropsychological Enigma
Author Affiliations
  • Ruth A. Huebner, MS, OTR, is Associate Lecturer, Department of Therapeutic Science, University of Wisconsin–Madison, 1087 Medical Science Center, 1300 University Avenue, Madison, Wisconsin 53706–1532
Article Information
Autism/Autism Spectrum Disorder / Research
Research Article   |   June 01, 1992
Autistic Disorder: A Neuropsychological Enigma
American Journal of Occupational Therapy, June 1992, Vol. 46, 487-501.
American Journal of Occupational Therapy, June 1992, Vol. 46, 487-501.
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Autism is increasingly viewed as an expression of an unidentified neurological disorder. Because understanding of neurological dysfunction is basic to evaluation and treatment in occupational therapy, this article provides a comprehensive and critical review of the literature since 1985 concerning the neuropsychology of autistic disorder. The research is categorized into four basic types: (a) neuropsychological testing of functional abilities, (b) treatment studies based on neuropsychological hypotheses, (c) autistic-related diseases and genetic disorders, and (d) neuroanatomical and neurophysiological studies. The research shows a spectrum of neurological impairments within the brain stem, cerebellum, midbrain, and frontal lobe. These impairments are associated with deficits in socioemotional skills, sensory processing, motor planning, and cognitive flexibility. This research suggests that persons with autistic disorder need evaluation and treatment of a wide spectrum of functional deficits.