Occupational therapists are ethically bound to provide quality care to assist all people across the life course to engage in meaningful occupations. This sense of purpose, however, is challenged by institutional, systemic, and attitudinal barriers to equitable care for racial and ethnic minorities and other marginalized identities. Future practitioners must learn how to provide culturally appropriate care characterized by awareness, humility, and dexterity in client interactions. This guide offers information, strategies, and resources for enhancing learner knowledge, skills, and attitudes through intentional and effective curriculum design practices. It is intended to assist educators with integrating cultural awareness, humility, and dexterity into intended learning outcomes; course topics; formal, informal, and hidden curricula; teaching approaches; and instructional strategies.